Search results for "spiral [galaxies]"
showing 10 items of 33 documents
Severe pre-eclampsia is associated with alterations in cytotrophoblasts of the smooth chorion.
2016
Pre-eclampsia (PE), which affects ∼8% of first pregnancies, is associated with faulty placentation. Extravillous cytotrophoblasts (CTBs) fail to differentiate properly, contributing to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the smooth chorion portion of the fetal membranes. The results showed a significant expansion of the CTB layer. The cells displayed enhanced expression of stage-specific antigens that extravillous CTBs normally upregulate as they exit the placenta. Transcriptomics revealed the dysregulated expression of many genes (e.g. placental proteins, markers of oxidative stress). We confirmed an sPE-related incr…
Unveiling the environment and faint features of the isolated galaxy CIG 96 with deep optical and HI observations
2018
Context. Asymmetries in atomic hydrogen (HI) in galaxies are often caused by the interaction with close companions, making isolated galaxies an ideal framework to study secular evolution. The AMIGA project has demonstrated that isolated galaxies show the lowest level of asymmetry in their HI integrated profiles compared to even field galaxies, yet some present significant asymmetries. CIG 96 (NGC 864) is a representative case reaching a 16% level. Aims. Our aim is to investigate the HI asymmetries of the spiral galaxy CIG 96 and what processes have triggered the star-forming regions observed in the XUV pseudo-ring. Methods. We performed deep optical observations at CAHA1.23m, CAHA2.2m and V…
Nitric oxide synthase in identified olivocochlear projection neurons in rat and guinea pig.
1999
Nitric oxide (NO) is thought to be involved in the effects of amino acids at the level of cochlear hair cell afferents. Recently, the isoform of the NO-producing enzyme, neuronal NO synthase (nNOS), has been demonstrated in neuronal structures of the cochlea in rats and guinea pigs histochemically and immunohistochemically. To investigate the sources of cochlear NO, we injected Fluoro-Gold (FG) into the cochlea of rats and guinea pigs. Upon terminal uptake of the tracer and neuronal transport we observed FG in terminals at the base of inner (IHC) and outer hair cells (OHC) and in neurons of the spiral ganglion. Ganglion cells and terminals at the IHC were clearly nNOS-positive, while termin…
Monitoring of the prompt radio emission from the unusual supernova 2004dj in NGC2403
2005
Supernova 2004dj in the nearby spiral galaxy NGC2403 was detected optically in July 2004. Peaking at a magnitude of 11.2, this is the brightest supernova detected for several years. Here we present Multi-Element Radio Linked Interferometer Network (MERLIN) observations of this source, made over a four month period, which give a position of R.A. = 07h37m17.044s, Dec =+65deg35'57.84" (J2000.0). We also present a well-sampled 5 GHz light curve covering the period from 5 August to 2 December 2004. With the exception of the unusual and very close SN 1987A, these observations represent the first detailed radio light curve for the prompt emission from a Type II-P supernova.
High-resolution observations of SN 2001gd in NGC 5033
2005
We report on 8.4 GHz VLBI observations of SN2001gd in the spiral galaxy NGC5033 made on 26 June 2002 and 8 April 2003. Our data nominally suggests a relatively strong deceleration for the expansion of SN2001gd, but we cannot dismiss the possibility of a free supernova expansion. From our VLBI observations on 8 April 2003, we inferred a minimum total energy in relativistic particles and magnetic fields in the supernova shell of E_min =(0.3-14) 10^{47} ergs, and a corresponding equipartition average magnetic field of B_min = (50--350) mG. We also present multiwavelength VLA measurements of SN2001gd, which are well fit by an optically thin, synchrotron spectrum, partially absorbed by thermal p…
Gentamicin alters Akt-expression and its activation in the guinea pig cochlea
2015
Gentamicin treatment induces hair cell death or survival in the inner ear. Besides the well-known toxic effects, the phosphatidylinositol-3 kinase/Akt (PI3K/Akt) pathway was found to be involved in cell protection. After gentamicin application, the spatiotemporal expression patterns of Akt and its activated form (p-Akt) were determined in male guinea pigs. A single dose of 0.1 mL gentamicin (4 mg/ear/animal) was intratympanically injected. The auditory brainstem responses (ABRs) were recorded prior to application and 1, 2 and 7 days afterward. At these three time points the cochleae (n=10 in each case) were removed, transferred to fixative and embedded in paraffin. Seven ears were used as u…
Detection of deuterated molecules, but not of lithium hydride, in the z = 0.89 absorber toward PKS 1830−211
2020
Deuterium and lithium are light elements of high cosmological and astrophysical importance. In this work we report the first detection of deuterated molecules and a search for lithium hydride, 7LiH, at redshift z=0.89 in the spiral galaxy intercepting the line of sight to the quasar PKS1830-211. We used ALMA to observe several submillimeter lines of ND, NH2D, and HDO, and their related isotopomers NH2, NH3, and H2^18O, in absorption against the southwest image of the quasar, allowing us to derive XD/XH abundance ratios. The absorption spectra mainly consist of two distinct narrow velocity components for which we find remarkable differences. One velocity component shows XD/XH abundances that…
A Sample of Field Ellipticals
2003
Using well-defined selection criteria applied to the LEDA galaxy catalogue we have constructed a sample of elliptical galaxies that can be taken to lie in the field. Such criteria can easily be applied to theoretical simulations for direct comparison with observations. The variation of the number of `isolated' ellipticals with selection criteria is also investigated. A preliminary study of the environment of the field ellipticals shows that, in the mean, they are surrounded by a population of dwarf galaxies, out to projected radii of at least 500 kpc, with a radial density profile of $r^{-0.6\pm 0.2}$ and a luminosity function slope of $\alpha \sim -1.8$. The results are compared and contra…
Stereotomy of the Late-Medieval Mediterranean. Crossroads of Experimental Design
2015
This paper analyses some specific case studies of vault and spiral staircase construction built in Sicily in the 12th and 13th centuries during Norman and Swabian rule, as a site of experimenta-tion in the field of stereotomy. The list of such examples still extant (in Palermo some details of the cathedral, the muqarnas in the Zisa Palace and its palatine chapel – the first stone muqarnas in the Mediterranean -, in Syracuse and Catania the castles built during the reign of Frederick II, etc) must be considered in conjunction with similar constructions, now lost or ruined, especially by earthquakes (eg. the intriguing Hall of Syracuse and Mongialino Castle). Among these exam-ples are buildin…
The transient gravitational-wave sky
2013
Interferometric detectors will very soon give us an unprecedented view of the gravitational-wave sky, and in particular of the explosive and transient Universe. Now is the time to challenge our theoretical understanding of short-duration gravitational-wave signatures from cataclysmic events, their connection to more traditional electromagnetic and particle astrophysics, and the data analysis techniques that will make the observations a reality. This paper summarizes the state of the art, future science opportunities, and current challenges in understanding gravitational-wave transients.